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KMID : 0358819890160030415
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Journal of Korean Society of Plastic and Reconstructive Surgeons
1989 Volume.16 No. 3 p.415 ~ p.421
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HISTOLOGIC CHANGES OF RABBIT SKIN INDUCED BY PROGRESSIVE TISSUE EXPANSION
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Abstract
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Soft-tissue expansion is a new surgical technique of providing donor tissue in modem reconstructive surgery. This technique provides a quantity of tissue of similar color, texture, and hair bearing qualities for reconstruction of adjacent defects.
It is known that the expanded skin shows several constant histologic changes including the increase in collagen fibers and vascularity within dermis, and thinning of subcutaneous tissue and dermis.
In this study, the author observed serial histologic changes of rabbit skin induced by progressive tissue expansion up to excessive expansion of 6 times.
The results are as follows
1. Changes in the thickness of the epidermis was minimal until 3 times of expansion, but slight thinning was observed at excessive expansion state.
2. The thickness of the dermis was progressively decreased, and collagen fibers in the dermis was rapidly increased in early phase of expansion.
3. The vascularity in the dermis was also progressively increased.
4. The skin appendages showed no structural changes even in excessive expansion.
5. The panniculus camosus showed no atrophic changes and the thickness was maintained
in excessive expansion state.
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KEYWORD
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